The intern will develop skills in cell biology (cell culture, immunofluorescence, confocal imaging) and will be trained to use advanced biophysical tools (deformable hydrogel beads, atomic force microscopy).
The selected candidate will receive training in the following areas: molecular biology, cell biology, Xenopus micro-injection and micro-surgery, fluorescent confocal microscopy, video-microscopy, numerical image analysis.
The project aims at uncovering the molecular and cellular bases for Ubx and AbdA distinct motif usage.
The master project (M2) aims at characterizing the epithelial connectivity and collective behavior of the intestinal differentiated domain in homeostatic conditions or under challenging contexts.
During the Master’s project (M1 or M2), the student will use some of the techniques used in the laboratory to quantitatively interrogate the structure-function relationship underlying interallelic interactions.
During this master project (M2) the student will apply the above method to obtain proof of principle that targeting selected candidate genes can efficiently induce or suppress intramuscular adipose tissue formation.
During this M2 project, the student will work on a recently developed model of medulloblastoma in the chick embryo.
During this master project (M1 or M2), the student will analyze the dynamics of PRC1 dots during neuronal specification and maintenance by in vivo time-lapse imaging, and characterize the nature of these dots.
The M2 project will use state-of-the-art genomics profiling techniques, Drosophila genetics, imaging and molecular biology for studying the antagonistic transcriptional control and dysfunction of fat body lipid metabolism development.
The successful completion of the project will allow you to answer how mechanical tension is generated inside human myofibers by integrating intracellular molecular forces and extracellular mechanical environment.
