Our findings provide mechanistic insight into the mechanism by which TAFA4 reverses injury-induced mechanical hypersensitivity, by restoring normal spinal neuron activity, and highlight the considerable potential of TAFA4 as a treatment for injury-induced mechanical pain.
Lydia Kerkerian-Le Goff, Research Director at the CNRS and head of the Cellular Interactions, Neurodegeneration and Neuroplasticity team at the Marseille Institute of Developmental Biology (IBDM)
Through an international collaboration, using breast cancer as a biological paradigm, Flavio Maina Team publishes a work in the Theranostics journal exemplifying how specificity in targeting cell cycle regulators is essential for combinatorial cancer therapies.
Ardem Patapoutian shares the honours of his Nobel Prize with his former post-docs and students including Aziz Moqrich, Chronic pain : Molecular and cellular mechanisms
7 IBDM teams have received grants from the Agence Nationale pour la Recherche (ANR) in 2021. Congratulations to Vincent Bertrand, Harold Cremer, Pascale Durbec, André Le Bivic, Pierre-François
Jules Lavalou and Qiyan Mao from Thomas Lecuit’s team report that Toll-8 controls myosin-II planar polarity in Drosophila embryos and wing discs via a physical interaction with the GPCR Cirl/latrophilin.
We introduce a novel, user-friendly web-based tool ‘AnnoMiner’ to annotate and integrate epigenetic and transcription factor binding data.
The Habermann team has repurposed the concept of multilayer networks generally used to integrate different types of data.
Antoine Barrière and Amel Toudji-Zouaz in the Bertrand team developed a new method to image and quantify transcription in vivo.
This study published in Cell Death & Disease, conducted by the team of L. Kerkerian-Le Goff provides the first evidence for a role of the stress-induced protein TP53INP1 in the maintenance of neuronal homeostasis in ageing and Parkinson’s disease-related stress conditions.
